Dr. Tariq Ahmed's Group
With an increasing ageing population across the World (due to improvements in healthcare) a greater financial burden is placed on caring for the elderly. Interestingly, a majority of neurological disorders can be also classified as metabolic disorders, including Alzheimer’s disease (AD). We are currently exploring the use of several compounds (e.g. selenate, cholesterol, metformin) that has the potential to be useful not only for AD, but also for type 2 Diabetes and Autism spectrum disorders in various mouse models. We employ behavioural tests and in vitro methods: recording from hippocampal slices and monitoring plasticity and ion currents, before examining the tissue for molecular and biochemical changes.